USMLE Exam Questions

A 23-year-old woman comes to the physician for genetic counseling prior to conception. Her brother and maternal uncle had Duchenne muscular dystrophy (DMD) and died at the ages of...

A randomized controlled trial is conducted to assess the risk for development of gastrointestinal adverse effects using azithromycin compared with erythromycin in the treatment of...

A 35-year-old woman comes to the office because of a 3-day history of severe right back pain. She has not had any fever, chills, or weight loss. She has no history of major medical...

A 6-day-old breast-fed boy is brought to the emergency department by his mother because of poor weight gain and irritability since delivery, and a 2-hour history of vomiting. Physi...

A 14-year-old boy is brought to the physician because of a 2-day history of a sore throat and fever that peaks in the late afternoon. He also has a 1-week history of progressive fa...

In a cohort study of elderly women, the relative risk ratio for hip fractures among those who exercise regularly is 1.2 (95% confidence interval of 1.1 to 1.8). Which of the follow...

A 12-year-old boy is brought to the physician by his mother because of a 1-month history of pain below the left knee. His mother says, "He can usually walk around, but he hasn't be...

A 22-year-old woman comes to the office because of a 3-day history of cold symptoms and a 1- week history of progressive fatigue. Six weeks ago, she received a kidney transplant fr...

A new test to detect the presence of malarial antibodies by ELISA is evaluated in 100 patients with active untreated malaria proven by demonstration of blood- borne parasites and i...

A 30-year-old woman comes to the physician because of a 2-day history of abdominal pain. She has a history of recurrent upper respiratory tract infections, sinusitis, and pancreati...

A 52-year-old man is brought to the emergency department 30 minutes after he had an episode of chest pain radiating to his jaw while shoveling snow. His pulse is 80/min, and blood...

A technician wants to determine whether cytomegalovirus (CMV) DNA is present in the blood of a bone marrow transplant recipient. DNA purified from the leukocytes of the patient is...

A 16-year-old boy comes to the physician because of a rash on his left inner thigh that first appeared 2 days after he returned from a hunting trip with friends in Minnesota. A pho...

After being severely beaten and sustaining a gunshot wound to the abdomen, a 42-year-old woman undergoes resection of a perforated small bowel. During the operation, plastic recons...

A 51-year-old man comes to the office because of a 6-month history of a lump on his tongue that is interfering with his speech and eating; he also has had a 6.8- kg (15-lb) weight...

A 31-year-old woman comes to the physician because of a 2-week history of malaise, nausea, vomiting, and decreased appetite. She is a known user of intravenous heroin. She appears...

A 57-year-old man receives radiation therapy for a squamous cell carcinoma of the lung. Despite therapy, the tumor progressively increases in size, and he dies 6 months later. His...

A 55-year-old man comes to the physician for a routine physical examination. He is currently taking no medications. His pulse is 80/min, and blood pressure is 165/95 mmHg. Physical...

A 53-year-old man comes to the physician because of a 6-month history of intermittent blood in his stool. He has had no pain with defecation. Physical examination shows a 1-cm, vis...

A 59-year-old man is brought to the emergency department because of a 4-day history of nausea, vomiting, and diarrhea. He also has been confused and agitated during this period. He...

A 2-hour-old female who is born at 37 weeks' gestation has purple patches on her skin as well as hepatosplenomegaly and jaundice. A CT of the head is obtained which reveals periven...

A 24-year-old female comes to the physician due to urinary frequency and burning with urination. She is diagnosed with a urinary tract infection and prescribed ciprofloxacin. The m...

A 34-year-old female comes to the physician with nausea and abdominal pain. She indicates that the pain is epigastric and it improves with food intake. She also reports recent weig...

A 5-month-old male is brought to the physician by his parents due to twitching of his facial muscles. Review of his medical records reveals that he has previously been treated for...

A 15-year-old female is brought to the physician by her mother because she is concerned that she has not started menstruating. Physical examination reveals the patient's vagina is...

A 45-year-old female comes to the physician with joint pain, swelling and morning stiffness which improves with use. She also reports weight loss of 3 kg (6.6 lbs). Laboratory test...

A 45-year-old male who has a BMI of 42 kg/mֲ2 undergoes a myocardial perfusion scintigraphy due to frequent chest pain during strenuous activities. An angiogram had earlier reveale...

A 2-week-old male is brought to the physician by his mother due to labored breathing for the past day. She had a home delivery which she reports as uneventful but say she developed...

A 30-year-old prim gravid female at 16 weeks' gestation comes to the physician for a routine prenatal examination. She has no pre-existing medical conditions and thus far her pregn...

A 35-year-old male comes to the physician due to fatigue. He recently returned from a trip to Japan. Laboratory results are as follows: Hemoglobin `" 9 g/dL - Mean corpuscular volu...

A 35-year-old male comes to the physician due to fatigue. He recently returned from a trip to Japan. Laboratory results are as follows: Hemoglobin `" 9 g/dL - Mean corpuscular volu...

A 50-year-old male comes to the physician complaining of neck masses that have been increasing in size for the past six months. He denies having any fevers or night sweats. Physica...

A 1-week-old male is brought to the emergency department by his mother due to persistent crying and bloody diarrhea. She says he was delivered at 33 weeks' gestation and has been b...

A 19-year-old female is brought to the emergency department after she collapsed while jogging. She has a history of anorexia nervosa. When she regains consciousness, she says as sh...

A 40-year-old male comes to his physician due to progressive muscle weakness and paralysis. Over the next few years, his condition progresses to complete paralysis of all voluntary...

A 9-month-old male is evaluated for lactic acidosis and increased levels of serum alanine. He is diagnosed with pyruvate dehydrogenase complex deficiency and placed on a special di...

A 40-year-old male is brought to the emergency department due to progressive memory loss, confusion, and urinary incontinence. Laboratory studies reveal a CD4 cell count of 25/mmֲ3...

A 35-year-old male comes to the physician due to fatigue. He recently returned from a trip to Japan. Laboratory results are as follows: Hemoglobin `" 9 g/dL - Mean corpuscular volu...

A 45-year-old female comes to the physician with joint pain, swelling and morning stiffness which improves with use. She also reports weight loss of 3 kg (6.6 lbs). Laboratory test...

A 45-year-old male is brought to the emergency department by the police who found him wandering around a park at midnight. Physical examination reveals bilateral hand tremors. Labo...

A 61-year-old male is admitted to the hospital with worsening shortness of breath and fatigue. Physical examination reveals dullness to percussion and decreased breath sounds in th...

A 24-year-old female comes to the physician due to urinary frequency and burning with urination. She is diagnosed with a urinary tract infection and prescribed ciprofloxacin. The e...

A 35-year-old female comes to the physician due to headaches of two months' duration. She has no history of pre-existing medical illnesses. Vital signs are within normal limits. A...

A 17-year-old female is brought to the emergency department by her parents due to right foot pain. She denies recent trauma and has no history of major illnesses. She is physically...

A 65-year-old male who had a cholecystectomy at a local hospital experiences nausea and vomiting two days later. He is prescribed metoclopramide by the resident physician. Metoclop...

A 34-year-old female comes to the physician with nausea and abdominal pain. She indicates that the pain is epigastric, and it improves with food intake. She also reports recent wei...

A 27-year-old male comes to the physician with skin lesions as shown in the exhibit. Physical examination reveals soft tissue crepitus and the smell of decomposing tissue. The most...

An 18-month-old male is brought to the physician due to mental retardation and abdominal distention. Physical examination reveals enlargement of the liver and spleen. Fundoscopy re...

A 50-year-old male is brought to the emergency department due to an acute onset chest pain that radiates to his jaw. An ECG reveals ST segment elevation in leads II, III and a VF....

A 60-year-old male with a past medical history of hyperlipidemia and hepatic dysfunction comes to the physician for a routine examination. He states that he has had difficulty init...