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USMLE · Question #592

A 40-year-old male comes to his physician due to progressive muscle weakness and paralysis. Over the next few years, his condition progresses to complete paralysis of all voluntary muscles and he even

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Abnormal Processes

Question

A 40-year-old male comes to his physician due to progressive muscle weakness and paralysis. Over the next few years, his condition progresses to complete paralysis of all voluntary muscles and he eventually dies of respiratory failure. Microscopic examination of tissue obtained at autopsy shows that both upper and lower motor neurons are degenerated. Of the listed options, the location which would likely reveal the most marked neuronal loss is the

Options

  • Acaudate nucleus
  • Bcerebellum
  • Cglobus pallidus
  • Dspinal cord
  • Esubstantia nigra

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Topics

#ALS#upper and lower motor neurons#spinal cord degeneration#motor neuron disease
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