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USMLE · Question #594
A 40-year-old male is brought to the emergency department due to progressive memory loss, confusion, and urinary incontinence. Laboratory studies reveal a CD4 cell count of 25/mmֲ3. A MRI reveals mode
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Abnormal Processes
Question
A 40-year-old male is brought to the emergency department due to progressive memory loss, confusion, and urinary incontinence. Laboratory studies reveal a CD4 cell count of 25/mmֲ3. A MRI reveals moderate brain atrophy. Although the patient is admitted for treatment he eventually dies of disseminated aspergillosis. Microscopic examination of an autopsy specimen from his brain shows multifocal lymphohistiocytic infiltrates with numerous microglial nodules and scattered multinucleated giant cells. His histologic and MRI findings were most likely caused by
Options
- Aaspergillosis
- BHIV encephalitis
- Cmycobacterial infection
- Dprogressive multifocal leukoencephalopathy
- Evacuolar myelopathy
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Topics
#HIV encephalitis#multinucleated giant cells#microglial nodules#AIDS dementia