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USMLE · Question #586

A 30-year-old prim gravid female at 16 weeks' gestation comes to the physician for a routine prenatal examination. She has no pre-existing medical conditions and thus far her pregnancy has been uncomp

The correct answer is B. hydatidiform mole. Although this patient has high blood pressure and proteinuria, one of the major diagnostic criteria for preeclampsia is onset of symptoms after 20 weeks of gestation. Development of these symptoms before the 20 week of pregnancy is suggestive of the presence of a hydatidiform mol

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Question

A 30-year-old prim gravid female at 16 weeks' gestation comes to the physician for a routine prenatal examination. She has no pre-existing medical conditions and thus far her pregnancy has been uncomplicated. She currently takes prenatal vitamins and iron supplements. Vitals reveal a blood pressure of 160/110 mmHg. Urinalysis reveals 3+- proteinuria. The most likely cause of these findings is

Options

  • Aanencephaly
  • Bhydatidiform mole
  • Cmaternal renal disease
  • Dneural tube defects
  • Etwin gestation

How the community answered

(17 responses)
  • A
    12% (2)
  • B
    82% (14)
  • D
    6% (1)

Explanation

Although this patient has high blood pressure and proteinuria, one of the major diagnostic criteria for preeclampsia is onset of symptoms after 20 weeks of gestation. Development of these symptoms before the 20 week of pregnancy is suggestive of the presence of a hydatidiform mole which is a form of gestational th trophoblastic disease characterized by "early pre-eclampsia," uterine enlargement, vaginal bleeding, passage of soft, edematous, grapelike tissue and significantly elevated beta-human chorionic gonadotropin (beta-hCG). Hydatidiform moles may be either complete moles or partial moles. The diagnosis may be made by ultrasound, but definitive diagnosis is confirmed by histopathologic examination. Treatment is with methotrexate, dilation

Topics

#hydatidiform mole#gestational trophoblastic disease#early hypertension in pregnancy#proteinuria

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