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USMLE · Question #589

USMLE Question #589: Real Exam Question with Answer & Explanation

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Question

A 50-year-old male comes to the physician complaining of neck masses that have been increasing in size for the past six months. He denies having any fevers or night sweats. Physical examination reveals bilateral, nontender cervical lymphadenopathy and hepatosplenomegaly. Biopsy of a cervical node reveals architectural distortion of the lymph node with proliferation of enlarged germinal follicles. Flow cytometry reveals a predominant cell population of CD, CD and CD - cells. The most likely cause of these findings is

Options

  • Abcl-2 activation
  • Bbcl-16 activation
  • Cc-myc activation
  • Dt(8;14)
  • Et(9;22)

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