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USMLE · Question #291

A drug ending in the suffix (tidine) is considered a ______.

The correct answer is D. H antagonist. Drugs ending in -tidine are H2 (histamine-2) receptor antagonists, making D correct. Examples like ranitidine, famotidine, and cimetidine all block H2 receptors in the stomach to reduce acid secretion. Antidepressants (A) use suffixes like -xetine or -triptyline; protease…

Principles of Therapeutics

Question

A drug ending in the suffix (tidine) is considered a ______.

Options

  • AAntidepressant
  • BProtease inhibitor
  • CBeta antagonist
  • DH antagonist

How the community answered

(22 responses)
  • A
    14% (3)
  • B
    5% (1)
  • C
    5% (1)
  • D
    77% (17)

Explanation

Drugs ending in -tidine are H2 (histamine-2) receptor antagonists, making D correct. Examples like ranitidine, famotidine, and cimetidine all block H2 receptors in the stomach to reduce acid secretion. Antidepressants (A) use suffixes like -xetine or -triptyline; protease inhibitors (B) end in -navir; and beta antagonists (C) end in -olol - none of which match -tidine. Memory tip: Think "histidine" - the amino acid histidine shares the root, reminding you that -tidine drugs work on histamine receptors.

Topics

#Drug nomenclature#H2 antagonists#Pharmacology#Acid suppression

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