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USMLE · Question #533

A 17-year-old girl has never had a menstrual period. Physical examination shows a normal female body habitus, normal breast development, and normal appearing external genitalia. She has no axillary…

The correct answer is A. Androgen insensitivity. See the full explanation below for the reasoning.

Question

A 17-year-old girl has never had a menstrual period. Physical examination shows a normal female body habitus, normal breast development, and normal appearing external genitalia. She has no axillary or pubic hair. The patient refuses to have a pelvic or rectal examination. Which of the following is the most likely explanation for the clinical presentation?

Options

  • AAndrogen insensitivity
  • BCongenital adrenal hyperplasia
  • CEctodermal dysplasia
  • DA psychiatric disorder
  • EA sex chromosome mosaicism

How the community answered

(30 responses)
  • A
    73% (22)
  • B
    3% (1)
  • C
    7% (2)
  • D
    3% (1)
  • E
    13% (4)

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