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USMLE · Question #534

USMLE Question #534: Real Exam Question with Answer & Explanation

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Question

A 12-year-old girl is brought to the physician because of a 2-month history of intermittent yellowing of the eyes and skin. Physical examination shows no abnormalities except for jaundice. Her serum total bilirubin concentration is 3 mg/dL, with a direct component of 1 mg/dL. Serum studies show a haptoglobin concentration and AST and ALT activities that are within the reference ranges. There is no evidence of injury or exposure to toxins. Which of the following additional findings is most likely in this patient?

Options

  • ADecreased activity of UDP glucuronosyltransferase
  • BGallstones
  • CIncreased hemolysis
  • DIncreased serum alkaline phosphatase activity
  • EIneffective erythropoiesis

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