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USMLE · Question #499

A sexually active 23-year-old man with multiple sex partners has dysuria and a yellow urethral exudate. Gram stain of the exudate shows numerous neutrophils, many that contain intracellular…

The correct answer is A. Antigenic variation. See the full explanation below for the reasoning.

Question

A sexually active 23-year-old man with multiple sex partners has dysuria and a yellow urethral exudate. Gram stain of the exudate shows numerous neutrophils, many that contain intracellular gram-negative diplococci. He has had three similar episodes of urethritis over the past 2 years. Which of the following properties of the infecting organism best explains the reinfection?

Options

  • AAntigenic variation
  • BCatalase
  • CInhibition of B-lymphocyte function
  • DInhibition of T-lymphocyte function
  • EPolysaccharide capsule

How the community answered

(17 responses)
  • A
    71% (12)
  • B
    12% (2)
  • C
    12% (2)
  • E
    6% (1)

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