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USMLE · Question #487
USMLE Question #487: Real Exam Question with Answer & Explanation
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Question
A couple comes for preconceptional genetic counseling because they both have a family history of -thalassemia. The woman has a minimally decreased hemoglobin concentration. Genetic studies show a single gene deletion. The man has microcytic anemia and a two-gene deletion. If the two-gene deletion is in trans (one deletion on the maternal gene and one deletion on the paternal gene), which of the following percentages of their offspring will have a two-gene deletion?
Options
- A0%
- B25%
- C50%
- D75%
- E100%
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