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USMLE · Question #541
USMLE Question #541: Real Exam Question with Answer & Explanation
The correct answer is A. Fatty acid oxidation. See the full explanation below for the reasoning.
Question
Six healthy subjects participate in a study of muscle metabolism during which hyperglycemia and hyperinsulinemia is induced. Muscle biopsy specimens obtained from the subjects during the resting state show significantly increased concentrations of malonyl-CoA. The increased malonyl- CoA concentration most likely directly inhibits which of the following processes in these subjects?
Options
- AFatty acid oxidation
- BFatty acid synthesis
- CGluconeogenesis
- DGlycogenolysis
- EGlycolysis
- FOxidative phosphorylation
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