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USMLE · Question #482
USMLE Question #482: Real Exam Question with Answer & Explanation
The correct answer is E. Separation of endothelial junctions. See the full explanation below for the reasoning.
Question
A 35-year-old man comes to the physician because of pain and swelling of his right arm where he scraped it on a tree branch 2 days ago. His temperature is 38.3°C (101°F). Examination of the right forearm shows edema around a fluctuant erythematous lesion at the site of trauma. The area is extremely tender to palpation. Which of the following is most likely the primary mechanism of the development of edema in this patient?
Options
- ADegranulation of eosinophils
- BDisruption of vascular basement membranes
- CIncreased hydrostatic pressure
- DRelease of thromboxane
- ESeparation of endothelial junctions
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