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USMLE · Question #612

A group of research scientists are studying immunohistochemical stains used for detecting the different types of cell. The stain which is used to detect epithelial cells is:

The correct answer is B. cytokeratin. Cytokeratin is a keratin-containing intermediate filament found in the intracytoplasmic cytoskeleton of epithelial tissue. In the cytoplasm, the keratin filaments form a complex network which extends from the surface of the nucleus to the cell membrane. The cytokeratin stain is…

Normal Structure and Function

Question

A group of research scientists are studying immunohistochemical stains used for detecting the different types of cell. The stain which is used to detect epithelial cells is:

Options

  • Achromogranin
  • Bcytokeratin
  • Cdesmin
  • Dneurofilaments
  • Evimentin

How the community answered

(30 responses)
  • A
    3% (1)
  • B
    80% (24)
  • C
    7% (2)
  • D
    10% (3)

Explanation

Cytokeratin is a keratin-containing intermediate filament found in the intracytoplasmic cytoskeleton of epithelial tissue. In the cytoplasm, the keratin filaments form a complex network which extends from the surface of the nucleus to the cell membrane. The cytokeratin stain is used to detect epithelial cells and tumors.

Topics

#immunohistochemistry#cytokeratin#epithelial cell markers#tumor pathology

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