USMLE · Question #418
USMLE Question #418: Real Exam Question with Answer & Explanation
The correct answer is C. Neural crest. The infant has Hirschsprung disease, which is due to an absence of ganglion cells in the wall of the colon. Neural crest cells contribute to the formation of many adult structures. Among these are all of the postganglionic neurons of the autonomic nervous system and the sensory n
Question
Options
- AEctoderm
- BEndoderm
- CNeural crest
- DNeural ectoderm
- ESplanchnic mesoderm
Explanation
The infant has Hirschsprung disease, which is due to an absence of ganglion cells in the wall of the colon. Neural crest cells contribute to the formation of many adult structures. Among these are all of the postganglionic neurons of the autonomic nervous system and the sensory neurons of the peripheral nervous system. Ectoderm forms the epidermis of the skin and the parenchymal cells of glands associated with the skin, such as the sweat glands, sebaceous glands, and mammary glands. Endoderm forms the epithelial lining of the gut tube and the parenchymal cells of glands associated with the gut tube, such as the liver and pancreas. Neural ectoderm forms the CNS, the somatic motor neurons of the peripheral nervous system, and the preganglionic neurons of the autonomic nervous system. Splanchnic mesoderm forms the visceral peritoneum, the visceral pleura, the visceral pericardium, and the stroma and muscle of the wall of the gut, among other structures.
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