USMLE · Question #109
Which of the following arteries is the most frequent site of coronary artery stenosis?
The correct answer is C. LAD. The Left Anterior Descending (LAD) artery is the most common site of coronary artery stenosis because it supplies a large territory of the left ventricle - including the anterior wall and interventricular septum - making it the most hemodynamically critical and clinically…
Question
Which of the following arteries is the most frequent site of coronary artery stenosis?
Options
- ALCA
- BRCA
- CLAD
- DPD
How the community answered
(48 responses)- A2% (1)
- B6% (3)
- C81% (39)
- D10% (5)
Explanation
The Left Anterior Descending (LAD) artery is the most common site of coronary artery stenosis because it supplies a large territory of the left ventricle - including the anterior wall and interventricular septum - making it the most hemodynamically critical and clinically significant vessel, earning its nickname "the widow maker."
- A (LCA/Left Main): The left main coronary artery is a short trunk that quickly bifurcates; significant disease here is serious but far less frequent than LAD disease.
- B (RCA): The right coronary artery is commonly diseased but ranks second to the LAD in stenosis frequency.
- D (PD/Posterior Descending): The posterior descending artery is a branch (usually of the RCA), not a primary vessel, and is not the leading site of stenosis.
Memory tip: Think "LAD = Leading Artery for Disease" - it's the most important and most frequently obstructed, which is why LAD occlusion causes the classic anterior ST-elevation MI.
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