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NCLEX-RN · Question #164

The nurse is assessing and getting a history from a client treated for depression with a monoamine oxidase (MAO) antidepressant. The most serious side effect associated with this antidepressant and…

The correct answer is A. Hypertensive crisis. (A) The most serious adverse reactions of MAO inhibitors involve blood pressure and ingestion of tyramine-containing foods, which may provoke a hypertensive crisis. (B) MAO inhibitors cause adverse reactions affecting the central nervous system and serious adverse reactions…

Physiological Integrity: Pharmacological and Parenteral Therapies

Question

The nurse is assessing and getting a history from a client treated for depression with a monoamine oxidase (MAO) antidepressant. The most serious side effect associated with this antidepressant and the ingestion of tyramine in aged foods may be:

Options

  • AHypertensive crisis
  • BSevere rash
  • CSevere hypotension
  • DSevere diarrhea

How the community answered

(52 responses)
  • A
    94% (49)
  • C
    2% (1)
  • D
    4% (2)

Explanation

(A) The most serious adverse reactions of MAO inhibitors involve blood pressure and ingestion of tyramine-containing foods, which may provoke a hypertensive crisis. (B) MAO inhibitors cause adverse reactions affecting the central nervous system and serious adverse reactions involving blood pressure. (C) MAO inhibits false neurotransmitters (phenylalanines) and may produce hypotensive reactions from gradual accumulation of these neurotransmitters. (D) The most serious adverse reactions of MAO inhibitors involve blood pressure.

Topics

#MAO inhibitors#tyramine interaction#hypertensive crisis#drug-food interaction

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