Which of the following application models runs the interface separately on a client machine?

A one-tier application, also known as a monolithic application, runs all its components, including the interface, logic, and data, on a single machine or server.

A two-tier application typically involves a client that combines the interface and some logic directly interacting with a server for data, but the separation of the interface isn't as distinct or formal as in a three-tier model.

In a three-tier application architecture, the presentation layer, containing the user interface, is explicitly separated to run on a client machine, while the business logic and data access layers typically reside on separate server-side tiers.

An n-tier architecture is a generalization of the three-tier model, encompassing three or more layers, but 'three-tier' specifically describes the common model where the client-side interface is a distinct layer.